Apoptosis

Apoptosis or Programmed Cell Death is basically cellular suicide. Apoptoza ili programirana stanična smrt je u osnovi stanični samoubojstvo. This interesting and very important cellular phenomena is the topic of this website. Ovo zanimljivo i vrlo važan stanični pojava je tema ove web stranice.

Apoptosis is the term given when programmed cell death (PCD) occurs in multicellular organisms. Apoptosis je mandat dao kad programirana stanična smrt (PCD) pojavljuje se u multicellular organizama. Apoptosis is one of the main types of programmed cell death which involves a series of biochemical events leading to specific cell morphology characteristics and ultimately death of cells. Apoptoza je jedan od glavnih tipova programirana stanična smrt koja uključuje niz biokemijskih događanja vodi do određene karakteristike morfologije stanica i naposljetku smrt stanice. Characteristic cell morphology of cells undergoing apoptosis include blebbing, changes to the cell membrane such as loss of membrane asymmetry and attachment, cell shrinkage, nuclear fragmentation, chromatin condensation, and chromosomal DNA fragmentation. Karakteristični stanica morfologija stanice apoptoza koji uključuju blebbing, promjene na stanične membrane, kao što su gubitak membrana asimetrija i privitak, stanica stezanja, nuklearna fragmentacije, chromatin condensation, i kromosomske DNA fragmentacije. Apoptosis differentiates from necrosis as the processes associated with apoptosis in disposal of cellular debris do not damage the organism in apoptosis. Apoptosis differentiates iz nekroza kao procese povezane s apoptoza u raspolaganju za celularnu odlomci ne štete organizmu u apoptoza.

Necrosis is a form of traumatic cell death that results from acute cellular injury. Nekroza je oblik traumatskog stanična smrt da rezultati iz akutne stanični ozljede. Apoptosis in contrast to necrosis, confers advantages during an organism's life cycle. Apoptoza u kontrastu nekroza, confers prednosti tijekom jednog organizma je životni ciklus. For instance during the development of the fetus in the mother, the differentiation of fingers and toes occurs because cells between the fingers apoptose with the end result that the digits are separate. Na primjer za vrijeme razvoja i fetus u majke, diferencijaciji i prsti Prsti se pojavljuje jer stanice između prstiju apoptose s kraja rezultat da su odvojene znamenke. Approximately between 50 billion and 70 billion cells die each day due to apoptosis in the average human adult. Otprilike između 50 i 70 milijardi milijardi stanica umre svaki dan zbog apoptoza u prosjeku ljudska odrasla osoba. In a year, this amounts to the proliferation and subsequent destruction of a mass of cells equal to an individual's body weight. U godinu dana, to iznosi na proliferaciju i naknadno razaranje od mase jednake stanice na individualnoj tjelesne težine.

Since the 1990's research has increased substantially in the field of apoptosis. Od 1990's research znatno je porasla na području apoptoza. It has been shown that defective apoptotic processes in humans and animals are related to a variety of diseases. To je pokazalo da neispravan apoptotic procese u ljudi i životinja su vezane uz različite bolesti. Excessive apoptosis causes hypotrophy, such as in ischemic damage, whereas an insufficient amount results in uncontrolled cell proliferation, such as cancer. Prekomjerni apoptoza uzrokuje hypotrophy, kao što je u ischemic oštećenja, dok je jedan nedostatan iznos rezultata u nekontrolirano stanična proliferacija, kao što je rak.

Apoptosis in Cardiomyocytes Apoptoza u Cardiomyocytes

Cardiomyocyte Apoptosis - Primed for Cell-Death Cardiomyocyte Apoptosis - Primed za Cell Death -